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Published 13:46 6 Mar 2019 GMT
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Amy Acker[/caption]
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Amy Acker - who has previously starred in Suits, Angel and Person of Interest - will be playing Kathleen (or Kate) Shepherd during an Amelia-centric episode this season.
She's been mentioned before on the show, but has never actually made an appearance at Grey Sloan Memorial (or in Seattle, really).
Or, at least, not that fans have seen.
Like her siblings, Kathleen - or Kate - is a doctor. Her speciality is in psychiatry.
Derek's two other sisters - Liz and Nancy - have both made appearances on the show before.
Neve Campbell played Liz during an appearance in season 9, while Embeth Davidtz played Nancy in season 3.
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