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Published 11:30 12 Jun 2025 BST

A new blood test has been discovered to detect coeliac disease without consuming any gluten.
Research published in Gastroenterology discovered a new blood test targeting “gluten-specific T cells”, which aids in diagnosing coeliac disease.
According to the HSE, you must consume gluten for a diagnosis.
However, this new research found a “high accuracy” for coeliac disease when patients consume gluten, as well as those following a strict gluten-free diet.
According to the Independent, researchers are collaborating with Novoviah Pharmaceuticals to confirm the test accuracy “across diverse populations and gather real-world data”.
As per the Independent, Head of WEHI’s Coeliac Research Laboratory and Associate Professor Jason Tye-Din, said:
“There are likely millions of people around the world living with undiagnosed coeliac disease simply because the path to diagnosis is difficult, and at times, debilitating.”
“By eliminating the need for a gluten challenge, we’re addressing one of the biggest deterrents in current diagnostic practices.”
“This test could be a game-changer, sparing thousands of people the emotional and physical toll of returning to gluten. It's a major step towards faster, safer diagnosis.”
Coeliac disease is a condition in which the body’s immune system reacts to gluten, a protein found in wheat, barley, and rye, causing damage to the lining of the intestine, preventing the body from absorbing important nutrients.
Approximately 100,000 people are coeliac, according to the Coeliac Society of Ireland.
Symptoms can include constant mouth ulcers, crippling fatigue, stomach pain, regular bouts of diarrhoea, anaemia and weight loss.
As a result, people with coeliac disease have to avoid foods with gluten.
If left untreated, the disease can lead to severe complications such as malnutrition, osteoporosis, infertility, and an increased risk of certain types of cancer.
The Coeliac Society of Ireland is urging people to get tested if they suspect they’re coeliac.
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